Blood rune

Blood runes are used for wave spells, the most powerful offensive spells in the normal spellbook (discounting Ancient Magicks) in RuneScape. Blood runes are dropped by several monsters, like White Knights, and can be stolen from the blood chest in the Chaos Druid Tower north of Ardougne or purchased in the Magic Guild, Mage Arena, or from the Mage of Zamorak. They are also a rare drop from Guards.

Currently, blood runes cannot be crafted, however images for blood talismans and blood tiaras exist, and upon gaining level 77 Runecrafting, players receives a message saying that they can now craft blood runes, suggesting that blood runes may be made craftable in an update in the near future.