For the potion flask version, see Antipoison+ flask. For the barbarian mix, see Antipoison+ mix.
Antipoison+ detail

The antipoison+ is made by mixing a clean toadflax and a yew root in a vial of coconut milk, giving 155 Herblore experience. The potion requires level 68 Herblore. Four doses are created instead of the usual three.

The Antipoison+ cures poison, and provides a longer immunity than super antipoisons. This potion reduces poison damage by 100% for 518 seconds.

This is the first potion that requires coconut milk in place of water.

Price per Dose

Item GE price Price per dose
Antipoison+ (1) Antipoison+ (1) 762 762
Antipoison+ (2) Antipoison+ (2) 1,221 611
Antipoison+ (3) Antipoison+ (3) 2,981 994
Antipoison+ (4) Antipoison+ (4) 6,836 1,709
Antipoison+ flask (6) Antipoison+ flask (6) 23,762 3,960


Antipoison+ (4) Antipoison+ (4)
Herblore-Make-X GE icon
155 XP-6,836
Herblore Herblore level68
P2P icon Members onlyYes
Antipoison+ (unf)Antipoison+ (unf)1N/A-
Yew rootsYew roots1881881


This potion can be made into an antipoison+ flask by using at least six doses of it with a potion flask. Players do not need a specific level to turn potions into flasks.

Production cost

The data in this table is based on the Grand Exchange prices of a vial of coconut milk, herbs, and secondary ingredient(s). It is accurate assuming all three items are bought off of the Grand Exchange and the resulting potion is sold afterwards.

Material cost Profit/loss Profit/XP
11,351 -4,515 -29.13
Grimy toadflaxClean toadflax + Coconut milk + Yew roots = Antipoison+ (3) Grimy toadflax is cleaned to become clean toadflax added to coconut milk also mixed with yew roots to make antipoison+.

Antipoison protection comparison

  • Prices based on price for (3) dose potions. Expect some variation when buying potions decanted to other dose counts.
Antipoison Price/dose Seconds/dose Price/second
Antipoison (4) Antipoison 119.33 86 1.39
Super antipoison (4) Super antipoison 1,602 346 4.63
Antipoison+ (4) Antipoison+ 993.67 518 1.92
Antipoison++ (4) Antipoison++ 976.67 720 1.36
Sanfew serum (4) Sanfew serum 1,737 86 20.2

Drop sources

Antipoison+ potion (1)

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For an exhaustive list of all known sources for this item, see here.
Source Combat level Quantity Rarity

This potion is only dropped in doses of 1.


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