Blood essence

Blood essences are pocket slot items with combat benefits unlocked after River of Blood, made using potions and congealed blood. The ability to make them is unlocked by reading Haemalchemy (Vol. 2), obtained by speaking to Vanescula Drakan on top of Castle Drakan after completion of River of blood. Vanescula will then give one of them for free, this completes the achievement Paint it Red.

Blood essences are created with 1,000 charges (including the free one from Vanescula). Additional charges can be added by using more congealed blood - 10 charges each - to a maximum of 5,000 charges. Once the charges are completely exhausted, the benefits of the essence cannot activate, but it can still be worn. Upon death, if recovered from a gravestone and not protected, essences lose 1,000 charges. Destroying an essence also destroys all of its remaining charges.

Blood essences have 2 functions when worn in combat: a passive effect, which occurs randomly in combat with a weak benefit, and a much stronger version of the effect which can be activated at any time from a right-click option when worn. Activated effects have a 1 minute cooldown period where it cannot be activated again; this is shared over all essences - except the tireless blood essence, which has a 2 minute cooldown shared with adrenaline/replenishment potions instead. Each time the passive effect occurs, 1 charge is drained; each use of the active effect drains 50 charges.

Each passive occurrence costs 6.9 coins, and each activation costs 345 coins.

Essences

Blood essences are made by using 100 congealed blood on a specific potion. They also require a number of vyre corpse cremations.

Essence		Vyre corpses	Potion		Passive effect	Activated effect
	Vampyric blood essence	0		Super Zamorak brew (4)	Each melee hit dealt has a chance to heal 2.5% of damage dealt, to a maximum of 250 per hit	The next melee hit dealt within 20 seconds heals 25% of damage dealt, up to 2500
	Penance blood essence	100		Super Guthix rest (4)	Chance of taking 8% more damage (increased by a minimum of 4 and a maximum of 100), restoring prayer points for 25% of the extra damage taken	The next hit taken within 20 seconds deals 80% more damage (increased by a minimum of 200 and a maximum of 1000), restoring prayer points for 25% of the extra damage taken
	Aegis blood essence	200		Guthix balance (4)	Chance of reducing incoming damage by 5% (by a minimum of 5 and a maximum of 250)	The next hit taken within 20 seconds is reduced by 50% (by a minimum of 50 and a maximum of 2500)
	Reflecting blood essence	300		Super Saradomin brew (4)	Each hit taken has a chance to apply a 6-second buff which reflects 5% of damage taken, to a maximum of 250 per hit	The next hit taken within 20 seconds is 50% reflected (by a minimum of 50 and a maximum of 2500) in addition to applying the passive's 6-second buff
	Berserk blood essence	400		Weapon poison++ (4)	Each hit taken has a chance to apply a 14% + 2 level boost to the relevant offensive skill (based on main-hand weapon) for 4 seconds; stacks with boosting potions, but will not activate when under the effect of an overload (or variant)	Applies a 14% + 2 level boost to the relevant offensive skill (based on main-hand weapon) for 20 seconds; stacks with boosting potions, but will not activate when under the effect of an overload (or variant)
	Tireless blood essence	500		Super restore (4)	Chance of restoring adrenaline when a monster is killed; amount based on the monster's maximum life points - a maximum of 2% adrenaline restored	Instantly restores 15% adrenaline. Two-minute cooldown, shared with adrenaline/replenishment potions.

Similar effects

• Vampyric blood essence: (superior) scrimshaw of vampyrism, vampyrism aura
• Penance blood essence: penance aura
• Aegis blood essence: aegis aura, Anticipation, Immortality
• Reflecting blood essence: deathtouch bracelet, Reflect, Deflect Melee/Magic/Missiles
• Berserk blood essence: grand potions, berserker/maniacal/reckless auras
• Tireless blood essence: ring of death, adrenaline potion

Cost

Using Grand Exchange as base price, the following table shows the cost to produce each blood essence:

Primary	Cost	Secondary	Cost	Total	Result
Super Zamorak brew (4)	7,839	100 x  Congealed blood	6,900	14,739	Vampyric blood essence
Super Guthix rest (4)	6,900			13,800	Penance blood essence
Guthix balance (4)	2,683			9,583	Aegis blood essence
Super Saradomin brew (4)	69,152			76,052	Reflecting blood essence
Weapon poison++ (4)	21,610			28,510	Berserk blood essence
Super restore (4)	2,798			9,698	Tireless blood essence