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This article has a calculator here. Calculators determine experience and costs based on real-time prices from the Grand Exchange Market Watch.
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Combination potions are unlockable potion recipes that were released with the second batch of the Prifddinas updates on 10 November 2014. There are 26 combination potions in total. All of them need to be unlocked by purchasing the recipe from the Recipe Shop in Meilyr Clan district, with prices from 100,000 coins to 1,000,000 coins, and nine have the additional requirement of finding unreadable pages in Daemonheim first, similar to unlocking a Fremennik Saga. Buying all recipes will cost the player a total of 11,500,000 coins.
There are no level requirements to purchase recipes. Thus, players can use Herblore boosts to make these combination potions.
There are four ways to obtain a potion recipe:
- Finding a page on the ground after opening a dungeon door. At 120 Dungeoneering, there is a 1/320 chance on normal floors and 1/107 chance on hard mode floors
- 100% chance by opening a door after triggering a Consistent yak card or Consistent yak card (team)
- As a common reward from the Motherlode Maw
- Buyable for 500,000 tokens from the Dungeoneering reward shop
To make a combination potion, players need a 4-dose vial of each component potion, as well as a crystal flask in their inventory. Using one potion on another will create a 6-dose flask of the combination potion.
Partially-used combination potions of the same type can be combined, by using one on the other. For example, you can combine a 1-dose potion with a 4-dose potion, to get a 5-dose potion. One of the crystal flasks will break in the process. NPCs that decant regular potions don't recognise these types of potions, but Teplin Macagan (near the Oo'glog bank) can decant them.
Combination potions benefit partially from portable wells; they can have their experience increased and ingredients saved, but they cannot produce a second potion.
Types of combination potions[]
| Potion |  Level
|
Unlock | Components | Effect | Cost |
|---|---|---|---|---|---|
 Grand strength potion
|
75 | 100,000 |  Super strength Strength potion
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Temporary Strength level boost of 14%+2. | 21,846 |
 Grand ranging potion
|
76 | 100,000 |  Super ranging potion Ranging potion
|
Temporary Ranged level boost of 14%+2. | 34,932 |
 Grand magic potion
|
77 | 100,000 |  Super magic potion Magic potion
|
Temporary Magic level boost of 14%+2. | 19,993 |
 Grand attack potion
|
78 | 100,000 |  Super attack Attack potion
|
Temporary Attack level boost of 14%+2. | 9,992 |
 Grand defence potion
|
79 | 100,000 |  Super defence Defence potion
|
Temporary Defence level boost of 14%+2. | 16,139 |
 Super melee potion
|
81 | 150,000 unreadable page
|
Super defence Super strength Super attack
|
Temporary boost to Attack, Strength and Defence levels of 12%+2. | 42,003 |
 Super warmaster's potion
|
85 | 200,000 unreadable page
|
Super ranging potion Super magic potion Super defence Super strength Super attack
|
Temporary boost to Magic, Ranged, Attack, Strength and Defence levels of 12%+2. | 87,948 |
 Replenishment potion
|
87 | 200,000 |  Adrenaline potion Super restore
|
Regain 25% adrenaline, restores all skills by 25%+8, and restores 25%+80 Prayer points. | N/A |
 Wyrmfire potion
|
89 | 200,000 |  Super antifire Antifire
|
Complete protection from dragon and wyvern fire for 6 minutes. | N/A |
 Enhanced replenishment potion
|
90 | 0 (unlocked with replenishment potion) |
Replenishment potion Adrenaline crystal
|
Regain 30% adrenaline, restores all skills and Summoning points by 25%+8, and restores 25%+80 Prayer points. | N/A |
 Extreme brawler's potion
|
91 | 300,000 unreadable page
|
 Extreme attack Extreme defence Extreme strength
|
Temporary boost to Attack, Strength and Defence levels of 15%+3. | N/A |
 Extreme battlemage's potion
|
91 | 300,000 unreadable page
|
 Extreme magic Extreme defence
|
Temporary boost to Magic and Defence levels of 15%+3. | N/A |
 Extreme sharpshooter's potion
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91 | 300,000 unreadable page
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 Extreme ranging Extreme defence
|
Temporary boost to Ranged and Defence levels of 15%+3. | N/A |
 Extreme warmaster's potion
|
93 | 400,000 unreadable page
|
Extreme attack Extreme defence Extreme strength Extreme ranging Extreme magic
|
Temporary boost to Attack, Strength, Defence, Ranged, and Magic levels of 15%+3. | N/A |
 Supreme strength potion
|
93 | 500,000 | Extreme strength Super strength
|
Temporary boost to Strength level of 16%+4. | N/A |
 Supreme attack potion
|
93 | 500,000 | Extreme attack Super attack
|
Temporary boost to Attack level of 16%+4. | N/A |
 Supreme defence potion
|
93 | 500,000 | Extreme defence Super defence
|
Temporary boost to Defence level of 16%+4. | N/A |
 Supreme magic potion
|
93 | 500,000 | Extreme magic Super magic potion
|
Temporary boost to Magic level of 16%+4. | N/A |
 Supreme ranging potion
|
93 | 500,000 | Extreme ranging Super ranging potion
|
Temporary boost to Ranged level of 16%+4. | N/A |
 Brightfire potion
|
94 | 600,000 |  Prayer renewal Super antifire
|
Restores 545 Prayer points over time and completely protects against dragon fire for 6 minutes. | N/A |
 Super prayer renewal potion
|
96 | 750,000 | Prayer renewal Prayer potion
|
Restores 25%+70 of total Prayer points as well as 595 Prayer points over the course of 6 minutes. | 16,953 |
 Holy overload potion
|
97 | 700,000 |  Overload Prayer renewal
|
Gives the effect of the overload potion for 6 minutes, with the buffs renewing every 15 seconds. Restores 545 Prayer points over 6 minutes. | N/A |
 Searing overload potion
|
97 | 700,000 | Overload Super antifire
|
Gives the effect of the overload potion for 6 minutes, with the buffs renewing every 15 seconds. Gives 6 minutes of complete dragonfire protection. | N/A |
 Overload salve
|
97 | 800,000 unreadable page
|
Overload Super antifire Antifire Prayer renewal Prayer potion Super antipoison
|
Temporary boost to Attack, Strength, Magic, Ranged and Defence level of 15%+3. Restores 555 Prayer points and protects from dragonfire, wyvern breath and poison over the course of 6 minutes. | N/A |
 Supreme overload potion
|
98 | 900,000 | Overload Super attack Super strength Super defence Super ranging potion Super magic potion
|
Temporary boost to Attack, Strength, Magic, Ranged and Defence level of 16%+4. | N/A |
 Supreme overload salve
|
99 | 1,000,000 unreadable page
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 Supreme overload potion Super antifire Antifire Prayer renewal Prayer potion Super antipoison
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Temporary boost to Attack, Strength, Magic, Ranged and Defence level of 16%+4. Restores 555 Prayer points and protects from dragonfire, and wyvern breath over the course of 6 minutes and reduces poison damage for 346 seconds. | N/A |
 Perfect plus potion
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99 | 1,000,000 unreadable page
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Overload Harmony moss Crystal tree blossom
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Gives the effect of all the perfect juju potions over a period of 4 hours. Does not affect combat stats. | N/A |
Scrapped combination potions[]
The following is a list of combination potions that were mentioned in the design documents and feedback threads, but were eventually scrapped before the release of Prifddinas:
