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The Giant Sea Snake is encountered at the end of the Royal Trouble quest. It is not as strong as its combat level suggests, but an antipoison potion, preferably super, is vital, as the snake is poisonous with damage starting in the nineties. It fights with melee up close and ranged from a distance, but it cannot detect the use of prayers. Like its offspring, it is vulnerable to slashing weapons.

The best way to defeat the snake is to attack it up close with melee, using a slashing weapon such as a Scimitar or an Abyssal whip to exploit its weakness. This way, it will not use its ranged attack, so players can freely use Protect from Melee to reduce the majority of the damage. Other factors such as what food to bring and what armour and weapon to use are left to the player's decision. It is recommended to bring at least lobsters or swordfish.

Drops

100% drops

Item Quantity Rarity GE price
Big bonesBig bones1Always196

Main drops

Item Quantity Rarity GE price
Watermelon seed 5Watermelon seed1Unknown1,649
Poison ivy seed 5Poison ivy seed1Unknown125
Guam seed 5Guam seed1Unknown78
Marrentill seed 5Marrentill seed1Unknown19
Tarromin seed 5Tarromin seed1Unknown45
Harralander seed 5Harralander seed1Unknown53
Toadflax seed 5Toadflax seed1Unknown1,547
Ranarr seed 5Ranarr seed1Unknown827
Irit seed 5Irit seed1Unknown530
Avantoe seed 5Avantoe seed1Unknown241
Kwuarm seed 5Kwuarm seed1Unknown9,210
Snapdragon seed 5Snapdragon seed1Unknown307
Cadantine seed 5Cadantine seed1Unknown1,057
Lantadyme seed 5Lantadyme seed1Unknown194
Dwarf weed seed 5Dwarf weed seed1Unknown334
Torstol seed 5Torstol seed1Very rare733
Adamant dart tipAdamant dart tip2Unknown414
Pearl bolt tips 5Pearl bolt tips3Unknown99
Broad arrow 5Broad arrow4UnknownNot sold
Water orbWater orb1Unknown2,380
Water runeWater rune15Unknown225
Mist runeMist rune1Unknown522
Fishing baitFishing bait50Unknown250
Raw bassRaw bass2Unknown1,224
Raw lobsterRaw lobster1Rare150
CasketCasket1Unknown2,960
Heavy boxHeavy box1Always[1]Not sold
Coins 25Coins23; 32; 44Unknown23–44
  1. ^ Dropped during Royal Trouble.

Tertiary drops

Item Quantity Rarity GE price
Sealed clue scroll (medium)Sealed clue scroll (medium)1UnknownNot sold
Long boneLong bone1UnknownNot sold
Giant snake spineGiant snake spine1Common[1]Not sold
  1. ^ Dropped during Fur 'n' Seek wish list.

Universal drops

Universal drops are dropped by nearly every monster outside of Daemonheim.
These drops are dropped alongside main drops.
Item Quantity Rarity GE price
Key tokenKey token1RareNot sold
Mimic kill tokenMimic kill token1Very rare8,889