Guthix may refer to:
- Guthix, a god
- Guthix (Gower Quest), an actor who plays Guthix in Gower Quest
- While Guthix Sleeps, RuneScape's first grandmaster quest
- Tears of Guthix, a members-only quest
- Tears of Guthix, a short Distraction and Diversion that rewards players with experience in their lowest skill
- Tears of Guthix, a music track unlocked during the eponymous quest
- The Tears of Guthix cavern, an area south of Lumbridge Swamp Caves
- Fist of Guthix, a safe minigame located in the Gamers' Grotto
- Edicts of Guthix, a series of decrees Guthix made to the world after the God wars
- Tribute to Guthix, a spring 2013 event
Weapons and armour[]
- Claws of Guthix, a spell that requires level 60 Magic
- Guthix staff, one of the three god staves
- Guthix cape, one of the three god capes
- God armour, which includes five items known collectively as Guthix armour
- Guthix crozier
- Guthix mitre
- Guthix mjolnir, a reward from Making History quest
- Green d'hide blessed set, an item set of Ranged armour aligned to the god Guthix consisting of:
- Guthix stole
Items[]
- Grapes of Guthix
- Guthix rest, a potion made during One Small Favour quest
- Guthix balance potion, a modified stat restore potion
- Items built in the chapel:
- Super Guthix rest
- Wine of Guthix