Is one of the Slayer masters, and you can obtain tasks from him. During While Guthix Sleeps, he is replaced by Achtryn. Once the quest is completed, Mazchna can once again be contacted with the use of this spell.
Is one of the Slayer masters, and you can obtain tasks from her. If you contact her at a bad time, as one of the monsters tries to escape from the dungeon, she will quite abruptly terminate the conversation, requiring another set of runes to contact her again.
Random will contact any of 26 other NPCs around RuneScape, and appears not to be "random" in that it cycles through 26 different NPCs, most of which are just amusing. The spell may start going in order randomly or just jump around. Using Random requires completion of Dream Mentor. These NPCs are:
If you stand right next to Murphy and contact him, he'll tell you that it's "so rude when you may as well just speak to him in person". There are similar responses when using NPC contact for most NPCs.
When contacting Bert the player will tell him he/she is totally "'armless", this is a reference to the quest Hand in the Sand.
If you try and contact Chuck using this spell while up in your clan's citadel and claim your penguin points it will say "Your call has been disconnected." This may happen for other NPCs who you wish to claim things from.
When casting the spell, the audio used sounds like tuning in an old radio, probably a humorous reference to the idea of 'tuning in' to the NPC.
When talking to the camel, you ask him "How am I speaking to you without a Camulet?", even if you have not done Enakhra's Lament, so you would not yet know what a camulet is.
After While Guthix Sleeps, attempting to contact Cyrisus used no runes and a message appeared that says "you take a moment to honour your fallen brethren, Cyrisus. Lucien will be made to pay." This no longer happens, and you cannot choose him at all. The reason for this change is unknown.
The prank conversation with Blurberry is a reference to a Simpsons episode where Bart prank calls Moe in a similar manner.
The spell cannot be used within a Clan Citadel or PvP grounds.
After completing The Mighty Fall, Zanik won't be contacted anymore, no matter if the player killed her or spared her.
After The Light Within, Islwyn replaces Eluned. He will recharge crystal seeds for players in her stead.