Nature may refer to:
- Nature rune, a rune used for transmutation spells
- Nature talisman, a talisman used to enter the nature altar
- Nature tiara, a tiara made by combining a nature talisman with a tiara
- Nature talisman staff, a talisman staff made with a nature talisman
- Nature staff, a Dungeoneering reward
- Amulet of nature, an amulet
- Nature Spirit, a quest that takes place in Morytania
- Nature Spirit, an NPC from the aforementioned quest
- Guthix, the god of nature and balance