The Nihil damage enhancer is a damage enhancers that can be received from the Motherlode Maw's daily random reward if the player has a total level of at least 2585. There is a chance of obtaining it by trading Wythien ten crystal motherlode shards. It can also be obtained by talking to Wythien to convert an unfocused damage enhancer to a Nihil damage enhancer. By converting an unfocused reward enhancer it will only have half of the charges, giving it 75 charges instead of 150.
When the enhancer is in the player's inventory, they will inflict 10% more damage against nihil. This lasts for 150 successful hits, after which the enhancer will disappear.