Equipment set effects are special effects that can be activated whe a player wears a full set of specific armour. There are a huge number of equipment sets within Runescape, and not all sets provide a bonus effect when worn. Examples of those that do can be found in any of the Barrows sets.
| Set | Members? | Effect |
|---|---|---|
| Barrows - dharok's set | Yes |
Wretched Strength - The lower the player's lifepoints, the higher their effective Strength. |
| Barrows - guthan's set | Yes | Infestation - Successful attacks have a chance of healing the wielder an amount of life points equal to the damage dealt. |
| Barrows - torag's set | Yes | Corruption - Successful melee attacks have a chance of lowering the victim's run energy by 20% similar to the abyssal whip special attack. |
| Barrows - verac's set | Yes | Defiler - Attacks have a chance of ignoring the target's armour and any active protection prayers, potentially causing heavy damage. |
| Barrows - ahrim's set | Yes | Blighted Aura - Successful magic attacks have a chance of lowering the enemy's Strength by five levels. |
| Barrows - karil's set | Yes | Tainted Shot - Successful ranged attacks have a chance of lowering the target's Agility level. |
| Barrows - akrisae's set | Yes | Doom - melee and magic attacks have a chance of restoring some of your prayer points |
| Battle robes | Yes | Chance the robes will supply Mind, Chaos, Death, or Blood Runes when casting a combat spell. Usually 12.5 %, but increased to 50% when combined with Staff of Light. |
| Druidic mage robes | No | Binding spells such as Bind, Snare, and Entangle have a higher chance of hitting the target. |
| Combat robes | No | Chance that the robes will supply any Mind, Chaos, Death, or Blood Runes when casting a combat spell. Usually 7.5 %, but increased to 20 % when combined with a Staff of Light. |