The Scroll of renewal requires a Prayer level of 65 and a Dungeoneering level of 65. Once used, this scroll will disappear, giving you the following permanent effect: you will gain the ability to use the Rapid Renewal prayer, which restores life points at 5 times the normal restore rate.
Examine Info: A scroll that surges with lifeforce.
When reading the scroll, you are given the message, "The secret is yours! You read the scroll and unlock the ability to use the Rapid Renewal prayer.
In the Items Kept On Death interface, it shows a value of 25,000 gp.