The potion is made through the Herblore skill, and requires a level of 52, and gives 6 experience when made. Players may use boosts such as Greenman's ale. The assist system cannot be used to make this potion.
Shrink-me-quick is a reference to "drink-me-quick", the label on a bottle of liquid that Alice drank in Lewis Carroll's Alice's Adventures in Wonderland that allows Alice to go into a very strange hole that takes her to Wonderland.
When a player tries to drink a shrink-me-quick potion outside the room with the mouse hole, the potion will not be consumed, but will instead play a unique animation.